Donor Testing and Screening

Initially our donors are selected by our sperm bank staff, based on a number of parameters:

Sperm Quality
Age
Personality
Education
Criminal Background Check
4 Generation Family Health History

Further screening includes blood and urine analysis:

Physical Exam every 6 months (including EKG)
Chemistry Panel
Complete Blood Count
Urinalysis
ABO-Rh Blood typing
HIV
HTLV I/II
Hemoglobin Fractionation
Hepatitis B Surface Antigen
Hepatitis B Core Antibody
Hepatitis C Viral Antibody
Syphilis
CMV IgG/IgM
Chlamydia
Gonorrhea

The genetic testing we do includes the following:

4┬ágeneration family medical history, which is reviewed by a trained genetic specialist┬áand a medical doctor (all donors)
Cystic Fibrosis screening
ΓåÆ┬á Up to 97 mutations on donors with optional advanced testing.
ΓåÆ ┬á32 standard mutations tested on all donors include:

G85E┬á┬á┬á┬á┬á ┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á A455E┬á┬á┬á ┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á S549N┬á┬á ┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á R1162X┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á 711+1 GΓåÆT

R117H┬á┬á ┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á ΓêåI507┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á S549R┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á W1282X ┬á ┬á ┬á ┬á ┬á ┬á ┬á2789+5 GΓåÆA

R334W┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á ΓêåF508┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á G551D ┬á ┬á ┬á ┬á ┬á ┬á ┬á ┬á N1303K ┬á ┬á ┬á ┬á ┬á ┬á ┬á 1717-I GΓåÆA

R347H┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á V520F┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á R553X ┬á ┬á ┬á ┬á ┬á ┬á ┬á ┬á ┬á394delTT ┬á ┬á ┬á ┬á ┬á ┬á 1898+1 GΓåÆA

R347P┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á G542X┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á┬á R560T ┬á ┬á ┬á ┬á ┬á ┬á ┬á ┬á ┬á3876delA ┬á ┬á ┬á ┬á ┬á ┬á 2183AAΓåÆG

2184delA ┬á ┬á ┬á ┬á ┬á ┬á3905insT ┬á ┬á ┬á ┬á ┬á ┬á1078delT ┬á ┬á ┬á ┬á ┬á ┬á621+1 GΓåÆT ┬á ┬á ┬á 3120+1 GΓåÆA

3659delC ┬á ┬á ┬á ┬á ┬á 3849+10kb CΓåÆT

Chromosome analysis (all donors)
Spinal Muscular Atrophy (SMA) (all donors)
Sickle Cell Disease. For all donors a┬áHemoglobin Fractionation┬áanalysis is done to detect this indirectly.
Thalassemia (all donors). A┬áHemoglobin Fractionation┬áanalysis is done to detect this indirectly. Please contact us if you would like to have your donor genetically screened for carrier status.
Bloom Syndrome (donors with Azhkenazi Jewish Ancestry)
Canavan disease (donors with Ashkenazi Jewish ancestry)
Familial Dysautonomia (donors with Ashkenazi Jewish ancestry)
Fanconi Anemia type C (donors with Ashkenazi Jewish ancestry)
Gaucher disease (donors with Ashkenazi Jewish ancestry)
Niemann-Pick type A disease (donors with Ashkenazi Jewish ancestry)
Tay-Sachs disease (donors with Ashkenazi Jewish or French Canadian ancestry)

Extended Genetic Testing:

Seattle Sperm Bank is proud to offer┬áCounsylΓÇÖs┬áUniversal Carrier Screening (102 conditions tested) on all donors who entered our program since August 2016!